PTEROIC ACID

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Quality products?make an important contribution to long-term revenue and profitability. Manufacturer supply top purity PTEROIC ACID 119-24-4 with ISO standards

1.What is the PTEROIC ACID ?

Pteroic acid is a key intermediate in the synthesis of folic acid analogues and derivatives, obtained through the chemical conversion of folic acid via acetylation and subsequent deacetylation steps, yielding a product often contaminated with residual folic acid. The process involves side reactions such as pyrazine derivative formation and pyrimidine ring opening, with purification achievable through column chromatography. Its structural features include a pteridine core linked to a benzoic acid moiety, making it a versatile precursor in medicinal chemistry.

2.What is the CAS number for PTEROIC ACID ?

The CAS number of PTEROIC ACID is 119-24-4.

3.What are another words for PTEROIC ACID ?

Synonyms?for?PTEROIC ACID 119-24-4:Benzoicacid, 4-[[(2-amino-1,4-dihydro-4-oxo-6-pteridinyl)methyl]amino]- (9CI); Benzoicacid, p-[[(2-amino-3,4-dihydro-4-oxo-6-pteridinyl)methyl]amino]- (6CI); Pteroicacid (7CI,8CI); NSC 14972; p-[(2-Amino-4-hydroxy-6-pteridylmethyl)amino]benzoicacid

4.What is PTEROIC ACID (119-24-4) used for?

Pteroic Acid (Methotrexate EP Impurity D N-Desmethyl Impurity) is a constituent as well as a degradation product of Folic Acid (F680300) formed via enzymatic hydrolysis. has been shown to activate the glutamylation of methotrexate by folylpolyglutamate synthetase.

InChI:InChI=1/C14H12N6O3/c15-14-19-11-10(12(21)20-14)18-9(6-17-11)5-16-8-3-1-7(2-4-8)13(22)23/h1-4,6,16H,5H2,(H,22,23)(H3,15,17,19,20,21)

Relevant articles related to PTEROIC ACID:

Article

Source

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Hultquist et al.

, p. 23 (1948)

A step-wise synthetic approach is necessary to access γ-conjugates of folate: Folate-conjugated prodigiosenes

Figliola, Carlotta,Marchal, Estelle,Groves, Brandon R.,Thompson, Alison

, p. 14078 - 14092 (2019/05/21)

Synthesis and analysis of bacterial folate metabolism intermediates and antifolates

Dawadi, Surendra,Kordus, Shannon L.,Baughn, Anthony D.,Aldrich, Courtney C.

supporting information, p. 5220 - 5223 (2017/11/06)

5.Buy PTEROIC ACID with the best price .

Shanghai Yolne Chemical Co., Ltd(expird) is a quality supplier of PTEROIC ACID. Our main goal is customer satisfaction. Contact us to negotiate the best price for your business on PTEROIC ACID 119-24-4.

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